Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22
نویسندگان
چکیده
منابع مشابه
CD4+ T Cells are Exhausted and Show Functional Defects in Chronic Lymphocytic Leukemia
Background: Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western world. This health problem is caused due to the accumulation of mature B-lymphocytes in the peripheral blood and bone marrow. In the course of cancer, CD4+ T cells become “exhausted” and characterized with poor effector functions and the expression of multiple inhibitory receptors. Objective: To inve...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2002
ISSN: 0014-2980,1521-4141
DOI: 10.1002/1521-4141(200205)32:5<1403::aid-immu1403>3.0.co;2-y